TL;DR
Noom has announced a new GRT test for its Med EPM program, which pairs behavioral changes with prescription GLP-1 medications. The test aims to evaluate the program’s effectiveness and expand access to medically supervised weight loss. Details on the test’s scope and timeline are still emerging.
Noom has announced the launch of a GRT (Genetic Risk Testing) trial for its Med EPM weight loss program, which combines behavioral therapy with prescription GLP-1 medications. The initiative aims to assess the program’s effectiveness and expand access to personalized, medically supervised weight management. The development is part of Noom’s effort to integrate genetic insights into weight loss strategies, though specific details about the trial’s scope and timeline remain undisclosed.
According to Noom, the GRT test is designed to evaluate the genetic factors influencing individual responses to weight loss treatments within the Med EPM program. The program itself pairs psychology-based behavioral modifications with FDA-approved GLP-1 medications such as Ozempic, Wegovy, Zepbound, and Mounjaro, which are delivered in a convenient, fully online format. Noom emphasizes that the GRT test is part of a broader effort to personalize weight loss plans, potentially improving outcomes by tailoring interventions to genetic profiles.
Details about the trial’s size, participant eligibility, and specific testing procedures have not yet been made public. Noom states that the test is currently in the pilot phase, with results expected to inform future expansion of the program. The company also notes that the GRT test will be offered alongside its existing services, which include clinical support, coaching, and a companion app designed to reinforce healthy habits. The initiative is FSA & HSA eligible, and medication is shipped within seven days of prescription approval.
Implications of GRT Integration in Weight Loss Programs
The introduction of a GRT test within Noom’s Med EPM program signals a move toward more personalized, genetics-informed weight management. If successful, this approach could enhance the effectiveness of combined behavioral and medication-based treatments, potentially setting a new standard in medically supervised weight loss. It also highlights the growing role of genetic testing in consumer health services, raising questions about accessibility, privacy, and the future of personalized medicine in weight management.

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Background on Noom’s Med EPM and Genetic Testing Trends
Noom’s Med EPM program combines behavioral therapy with prescription GLP-1 medications, which have gained popularity for their proven effectiveness in weight loss. The program is fully online, offering convenience and accessibility without in-person visits. The company has previously emphasized combining lifestyle changes with medication as a best practice, supported by a survey of primary care physicians recommending this approach.
Genetic testing for weight management has been a topic of increasing interest, with some studies suggesting that genetic factors influence individual responses to treatments like GLP-1 medications. However, the integration of GRT into commercial weight loss programs is still emerging, and regulatory and ethical considerations are ongoing. Noom’s move to incorporate GRT testing represents a significant step in this evolving landscape.
“The GRT test could help personalize weight loss treatments by identifying genetic factors that influence response to medications and behavioral strategies.”
— an anonymous researcher

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Details Still Emerging on GRT Test Scope and Impact
It is not yet clear how extensive the GRT testing will be, including participant eligibility, testing methods, and how results will influence treatment plans. The timeline for full implementation and whether the test will be available to all users or limited to specific groups remains uncertain. Additionally, the clinical validation and regulatory approval status of the GRT component are still to be clarified.

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Next Steps in GRT Test Development and Program Expansion
Noom plans to pilot the GRT test within select markets, with results expected to guide broader rollout. The company will likely publish findings from the trial, and further details on participant recruitment and testing procedures are anticipated in the coming months. Monitoring how the integration of genetic testing affects treatment outcomes will be crucial for assessing its future role in weight management.

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Key Questions
What is the purpose of the GRT test in Noom’s program?
The GRT test aims to identify genetic factors that influence individual responses to weight loss medications and behavioral strategies, enabling more personalized treatment plans.
Is the GRT test available to all Noom users now?
No, the GRT test is currently in a pilot phase, and it is not yet clear when or if it will be widely available.
How does Noom Med combine medication and behavioral therapy?
Users complete a clinical survey, receive a prescription if appropriate, and access ongoing support via the Noom app, which includes coaching, diet, exercise tracking, and medication management.
What medications are included in Noom Med’s program?
The program offers prescription GLP-1 medications such as Ozempic, Wegovy, Zepbound, and Mounjaro, with options for microdosing to reduce side effects.
What are the potential benefits of integrating GRT testing?
If effective, GRT testing could improve treatment outcomes by tailoring weight loss strategies to individual genetic profiles, potentially increasing success rates.
Source: Greatist